Melatonin 200 tablets

Indications
With sleep disorders, including those caused by a violation of the "sleep-wake" rhythm, such as desynchronosis (sudden change of time zones).

It has an adaptogenic, sedative, hypnotic effect. Normalizes circadian rhythms. Increases the concentration of gamma-aminobutyric acid (GABA) and serotonin in the midbrain and hypothalamus, changes the activity of pyridoxal kinase involved in the synthesis of GABA, dopamine and serotonin. Regulates the sleep-wake cycle, daily changes in locomotor activity and body temperature, has a positive effect on the intellectual and mnestic functions of the brain, on the emotional and personal sphere. Promotes the organization of biological rhythm and normalization of night sleep, has a hypnotic effect. Improves the quality of sleep, accelerates falling asleep, reduces the number of night awakenings, improves well-being after waking up in the morning, does not cause a feeling of lethargy, fatigue and fatigue when waking up. Makes dreams more vivid and emotionally intense.
Adapts the body to the rapid change of time zones, reduces stress reactions, regulates neuroendocrine functions. Adapts the body of weather-sensitive people to changes in weather conditions. It exhibits immunostimulating and antioxidant properties.
It does not cause addiction and dependence.

Composition:
Composition per tablet
Active ingredient: melatonin - 3.00 mg.
Excipients: microcrystalline cellulose - 172.72 mg, calcium hydrophosphate - 54.68 mg, sodium croscarmellose - 7.20 mg, colloidal silicon dioxide - 1.20 mg, magnesium stearate - 1.20 mg.
Shell excipients: hypromellose (hydroxypropylmethylcellulose) - 4.00 mg, titanium dioxide - 2.90 mg, polysorbate 80 - 1.32 mg, macrogol 4000 (polyethylene glycol 4000) - 0.89 mg, talc - 0.89 mg.

Method of administration and dosage
Inside.
In case of sleep disturbance - 3 mg once a day for 30-40 minutes before bedtime. With desynchronosis as an adaptogen when changing time zones - 1 day before the flight and in the next 2-5 days - 3 mg for 30-40 minutes before bedtime. The maximum daily dose is 6 mg.